Infinium MethylationEPIC Array Service V2.0
NEW Infinium MethylationEPIC Array V2.0
Infinium MethylationEPIC Array V2.0
The Infinium MethylationEPIC v2.0 Array Services (improved version of the EPIC v1.0) is the new cutting-edge genome-wide DNA methylation analysis technique from Illumina® based on bisulfite conversion. It allows to quantitatively detect the total methylation level of over 930,000 methylations sites throughout the human genome at single nucleotide resolution. It offers comprehensive coverage of CpG islands, enhancer regions, open chromatin sites and other important regions of the methylome with extended content compared to the EPIC v1.0.
Comprehensive and improved Genome-Wide Coverage
- Cost-effective solution with rapid turnaround time
- Improved Genome-Wide Coverage
- Over 930,000 CpGs detected in human samples at single nucleotide resolution
- High percentage of probe overlap with previous version and 150,000 newly covered CpGs
- More than 99% correlation in methylation values with EPIC v1.0
- Compatible with FFPE samples with additional mandatory DNA Restoration step
- End-to-end services include bisulfite conversion, array hybridization, array scan and data quality control
- Bioinformatic analysis offering: comparative analysis, data mining
Workflow
- Bisulfite conversion
- Whole genome amplification
- Array hybridization
- Single base extension
- Array scanner
Bioinfomatic analysis
Analysis |
Features |
| Standard | Standard files provided:
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| Differential methylation analysis | Identification of differentially methylated CpGs between sample groups.
Files provided:
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| Gene ontology terms analysis | Enrichment analysis on gene sets. Gene Ontology terms that are overrepresented in differentially bound regions may indicate the underlying biological processes involved. |
| Pathway analysis | Identify biochemical pathways in which genes associated with differentially methylated regions (or individual differentially methylated CpGs) may be overrepresented. |
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| G0209006 | Infinium MethylationEPIC Array Service V2.0 | Custom |
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